The neural processing of harmful stimuli is called nociception. Nociceptive pathways involve multiple actors in the peripheral and the nervous system. Each of these actors constitutes a putative target to design therapeutics. Calcitonin gene-related peptide (CGRP) has been identified as a key vasodilator neuropeptide involved in several pain and inflammation mechanisms.
It is important to be able to measure the levels of neuropeptides associated with nociceptive pathways such as CGRP. Bertin Bioreagent offers ELISA kits for CGRP quantification in complex human and rodent samples.
All you need to know about:
• Measurement of plasma CGRP level in Pediatric migraine patients
• Evaluation of ciguatoxin-induced CGRP release in mouse and rat skin preparations
• Measurement of CGRP release from mouse saphenous and vagus nerves