Bertin Bioreagent

[White paper]

Best practices for Prion detection in tissues and cells


Prions are misfolded proteins believed to be responsible for a wide variety of fatal neurodegenerative diseases. They can either enter the brain through infection or be produced by mutations. In mammals, no current therapies are known to be efficiently stop the propagation of prion aggregates in the nervous system. For this reason characterizing the behavior of prion strains is a crucial step to deepen our understanding of prion diseases. In this White Paper discover how Bertin Instruments supports prion research.

All you need to know about:

• Study of the degradation of chronic waste disease prions by humic acids
• Flow cytometry analysis of PrPC Knockdown by si RNA in hDPSCs
• Detection of two prion strains in the spleen and in the granuloma

Bertin Bioreagent

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