[White paper] Calcitonin gene-related peptide (CGRP) in complex biology matrices: Application to pain and inflammation studies

Calcitonin gene-related peptide (CGRP) has been identified as a key vasodilator neuropeptide involved in several pain and inflammation mechanisms. For example, it has been shown that CGRP is released during migraines and that increase in circulating CGRP levels can trigger migraines in patients. To understand the complex mechanisms involved in chronic pain conditions, it is important to be able to measure the levels of neuropeptides associated with nociceptive pathways such as CGRP. Bertin Bioreagent offers ELISA kits for CGRP quantification in complex human and rodent samples. Today, the Bertin Bioreagent CGRP kits are widely used by scientists and have been extensively cited in pain and inflammation studies.

All you need to know about:

• Measurement of plasma CGRP level in Pediatric migraine patients
• Evaluation of ciguatoxin-induced CGRP release in mouse and rat skin preparations
• Measurement of CGRP release from mouse saphenous and vagus nerves