[Application Note]
Efficient prevention of protein degradation by proteases with the Protein Safe Precellys Lysing kits

Homogenization of biological samples for protein extraction using Precellys® Evolution and Cryolys® Evolution ensures a high yield of protein recovery and prevents protein degradation from heat. Nonetheless, protein degradation can still occur as a result of the action of endogenous proteases, during and after the homogenization process. The use of protease inhibitors becomes hence key to ensure successful protein extraction for any type of downstream application.

In this Application Note, we highlight the use of the Protein Safe Precellys Lysing kits, a ready-to-use tool that contains an optimized cocktail of protease inhibitors to protect your samples from endogenous proteases in several types of tissue homogenates.